Which factors determine exocrine pancreatic dysfunction in diabetes mellitus?

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Exocrine pancreatic function in diabetes mellitus.

An investigation of serum immunoreactive trypsin concentration and pancreatic isoamylase activity in patients with diabetes mellitus has shown that exocrine pancreatic deficit is maximal in insulin dependent diabetics, intermediate in those controlled with sulphonylureas, and absent in patients controlled with biguanides or diet or both. A significant correlation between the serum concentration...

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Exocrine pancreatic function in diabetes mellitus

An investigation of serum immunoreactive trypsin concentration and pancreatic isoamylase activity in patients with diabetes mellitus has shown that exocrine pancreatic deficit is maximal in insulin dependent diabetics, intermediate in those controlled with sulphonylureas, and absent in patients controlled with biguanides or diet or both. A significant correlation between the serum concentration...

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Diabetes mellitus and exocrine pancreatic function.

lary circulation and thereby reduces islet perfusion. Interestingly, in tropical countries and India a special form of non-alcoholic tropical calcifying pancreatitis leads to DM. Although little is known about the exact etiology of this form of diabetes it has been found that the -cell function is damaged whereas the  cells are preserved [6, 7] . This is in contrast to the non-tropical chronic...

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Exocrine Pancreatic Insufficiency and Diabetes Mellitus

Gastrointestinal symptoms are common in patients with diabetes mellitus. One possible cause for these symptoms is exocrine pancreatic insufficiency, and although several hypotheses have been proposed to explain the aetiology, the precise pathophysiological mechanisms remain to be elucidated. The prevalence and the clinical importance of exocrine pancreatic insufficiency are debatable. Exocrine ...

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Alterations in Exocrine Pancreatic Function in Diabetes Mellitus

Despite being described anatomically almost 2,000 years ago the physiological function of the pancreas and its role in diseases remained more or less unknown until the 19 century. Performing pancreatectomies in dogs, von Mehring and Minkowski realised that the animals developed diabetes that could be cured by pancreas transplantation (26). Ever since these studies it has been accepted that panc...

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 2019

ISSN: 1007-9327

DOI: 10.3748/wjg.v25.i22.2699